Marla J. Berry, PhD
Associate Member, Cancer Biology Program, University of Hawaiʻi Cancer Center
Academic Appointment(s):
Professor and Director, Pacific Biosciences Research Center, University of Hawaiʻi at Mānoa
Degree(s):
PhD, Biochemistry and Molecular Biology, University of California, Santa Barbara
Award(s)
2006 - Scientist of the Year, Achievement Rewards for College Scientists Foundation
2004 - Mary Shorb Award Lecturer, University of Maryland
2001 - Ruth Pike Annual Lectureship in Human Nutrition, Pennsylvania State University
1999 - Van Meter Prize, American Thyroid Association
1998 - Nutrition Emphasis Week Visiting Professor, University of Missouri, Columbia
Research Focus
Our research focuses on the trace element, selenium, and the function of selenoproteins in antioxidant defense mechanisms and maintaining redox balance. We use cell culture, mouse models and ‘omics methods to investigate effects of manipulating dietary selenium and targeted genetic alterations of selenium metabolism, resulting in metabolic syndrome and impaired neurological function. We are also investigating the mechanisms underlying sexual dimorphism in selenium requirements and utilization.
Selected Publications
Lin Y, Collier A, Liu W, Berry MJ, and Panee J. (2008). The inhibitory effect of bamboo extract on the development of 7,12-Dimethylbenz[a]anthracene (DMBA)-induced breast cancer and its regulatory effect on sulfotransferase activity. Phytotherapy Research 22(11):1440-5. PMC4664529.
Squires J, and Berry MJ. (2006). Selenium, selenoproteins and cancer. Hawaii Medical Journal, 65, 239-40. PMID: 17004624.
Kumaraswamy E, Malykh A, Korotkov KV, Kozyavkin S, Hu Y, Kwon SY, Moustafa ME, Carlson BA, Berry MJ, Lee BJ, Hatfield DL, Diamond AM and Gladyshev VN. (2000). Structure-expression relationships of the 15 kDa selenoprotein gene: possible role of the protein in cancer etiology. J Biol Chem; 275, 35540-35547.
Publication list via PubMed
Active Grants
Berry MJ (PI)
NIH-NIGMS
P20 GM139753
COBRE: Integrative Center for Precision Nutrition and Human Health
03/20/2022 – 1/31/2027
