Christoph Rettenmeier, PhD
Associate Member, Population Sciences in the Pacific Program (Cancer Epidemiology), University of Hawaiʻi Cancer Center
Academic Appointment(s):
Assistant Professor (Assistant Researcher), Department of Medicine, John A. Burns School of Medicine, University of Hawaiʻi at Mānoa
Adjunct Assistant Professor, Department of Anatomy, Biochemistry & Physiology, University of Hawaiʻi at Mānoa
Degree(s):
PhD, Chemistry, University of Heidelberg, Germany
Postdoctoral, Chemistry, University of Heidelberg, Germany
Postdoctoral, Biomedical Engineering, University of Hawaiʻi at Mānoa
Honor(s)
2017 - Merit Abstract Award from the Organization of Human Brain Mapping
Research Focus
Dr. Rettenmeier is interested in the development of new imaging techniques and their application in disease. His major clinical focus is on the characterization of liver tissue in the context of metabolic liver disease as one of the leading causes of cirrhosis and cancer. He is involved in several research projects involving different medical imaging modalities, but his primary research focus is on the development of methods using Magnetic Resonance Imaging (MRI). Dr. Rettenmeier’s MRI projects cover structural and functional methodologies in brain and body and include the design of MR pulse sequences and model-based image reconstruction techniques. He is particularly interested in abdominal imaging techniques that enable the quantitative mapping of multiple MR parameters.
Selected Publications
Rettenmeier CA, Maziero D, Stenger VA. (2021). Three-dimensional radial echo planar imaging for functional MRI. Magn Reson Med; 87: 193– 206. PMCID: PMC8616809.
Rettenmeier C, Maziero D, Kai Tobias Block, Stenger VA. (2020). Simultaneous Multi-Slice Radial Echo Volumar Imaging for Fast Simultaneous Multi-Parametric Imaging, In: Proceedings of the 2020 ISMRM & SMRT Virtual Conference & Exhibition, Abstract 0622.
Evangelista EB, Kwee SA, Sato MM, Wang L, Rettenmeier C, Xie G, Jia W, Wong LL. (2019). Phospholipids are A Potentially Important Source of Tissue Biomarkers for Hepatocellular Carcinoma: Results of a Pilot Study Involving Targeted Metabolomics. Diagnostics (Basel);Oct 29;9(4). PubMed PMID: 31671805. PMCID: PMC6963224.
Rettenmeier C, Maziero D, Qian Y, Stenger VA. (2019). A circular echo planar sequence for fast volumetric fMRI. Magn Reson Med; 81: 1685– 1698. PMCID: PMC6347523.
Rettenmeier C, Stenger VA. (2019). Radiofrequency phase encoded half‐pulses in simultaneous multislice ultrashort echo time imaging. Magn Reson Med; 81: 3720– 3733. PMCID: PMC6435423.
Publication list via MyNCBI
Active Grants
C. Rettenmeier, Co-I; U. Lim, PI
NIMHD, NIH
R01 MD018265-01
"Longitudinal Study of Early NAFLD Progression and the Gut Microbiome in Asian Americans, Native Hawaiians and Whites"
To identify the kinds of gut bacteria and their metabolic pathways that are associated with increase in liver fat, more extensive liver stiffness, and increase in blood biomarker-based liver fibrosis over time in a prospective multiethnic study of underrepresented Asian Americans and Native Hawaiians, and Whites.
09/22 – 06/27
C. Rettenmeier, Co-I; S. Kwee, PI
NCI, NIH
R01CA262460-01
"Evaluation of treatment predictors reflecting beta-catenin activation in hepatocellular carcinoma"
This project comprises a phase 2 clinical trial to evaluate positron emission tomography/computed tomography (PET/CT) imaging and DNA sequencing based liquid biopsy as diagnostic tools for predicting resistance to immunotherapy in hepatocellular carcinoma.
07/01/21 – 06/30/26
C. Rettenmeier, RPL; M. Berry, PI
NIGMS, NIH
COBRE (#1P20GM139753-01A1)
"Integrative Center for Precision Nutrition and Human Health" The Overall Goal of this Centers of Biomedical Research Excellence Phase I proposal is the creation of an Integrative Center for Precision Nutrition and Human Health at the University of Hawai’i at Manoa.
Project title: A Novel Simultaneous Multiparametric MRI Approach for the Quantitative Assessment of Non-alcoholic Fatty Liver Disease Progression.
03/20/22 – 01/31/25
C. Rettenmeier, Co-I; A. Stenger, PI
NIBIB, NIH
R01 EB023618
"Radial Echo Volumar Imaging"
The purpose of this project is the development of a fast, motion-robust imaging strategy for functional MRI and dynamic imaging.
07/15/20 – 07/14/24
C. Rettenmeier, Co-I; T. Matsui, PI
Hawaii Community Foundation
MedRes_2022_ 00000771
"Cell-to-cell death along myofibers in ischemic heart disease"
To study the mechanism of cell-to-cell death along myofibers in ischemic heart disease using DTI MRI.
07/01/22 – 01/01/24
