Stephanie Si Lim, MD

Stephanie Si Lim, MD

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Associate Member, Cancer Biology Program, University of Hawaiʻi Cancer Center
Core Clinical Member, Translational and Clinical Research, University of Hawaiʻi Cancer Center

Academic Appointments:
Assistant Professor (Assistant Researcher), University of Hawaiʻi Cancer Center, University of Hawaiʻi at Mānoa
Assistant Clinical Professor, Department of Pediatrics, John A. Burns School of Medicine, University of Hawaiʻi at Mānoa

Degree(s):
MD, Georgetown University School of Medicine, Washington, DC

Professional Training

Hematology/Oncology Fellowship, Children's Hospital of Philadelphia, Philadelphia, PA
Fellowship Chief, Children's Hospital of Philadelphia, Philadelphia, PA
Pediatrics Residency, Children's Hospital of Philadelphia, Philadelphia, PA

Specialty Certification(s)

American Board of Pediatrics, Board certification in Pediatrics
Advanced Skills Training in Medical Education

Research Focus

Dr. Si Lim is an Associate Professor at the University of Hawaiʻi Cancer Center, and an Assistant Clinical Professor at Kapiʻolani Medical Center for Women & Children and John A. Burns School of Medicine. As a young translational clinical investigator, her research interest is to gain a better understanding of the immunologic topography in different ethnicities in order to provide foundational work for ethnic specific targeted immunotherapy.  Findings from her research will pave the way for future early phase clinical trials.

Selected Publications

Si SJ, Barrett DM. (2021). Characterization of Immuno-oncologic Landscape in Pediatric Cancers: Uniform TIM-3 and Galectin-9 Positivity on Immunohistochemistry Staining of Tumor Specimen at Diagnosis in Pediatric Patients with Ewing Sarcoma. Journal of Cancer Immunology; 3(3):163-176.

Si SJ, Grupp SA, Dinofia A. (2021). Tisagenlecleucel in the treatment of relapsed/refractory pediatric B-cell leukemia. Pediatric Blood Cancer; May; 68(9):e29123.

Si SJ, Tasian SK , Bassiri H, Fisher BT, Atalla J, Patel R, Romberg N, Lambert MP, Paessler M, Behrens EJ, Teachey DT, Sullivan KE. (2021) Diagnostic Challenges in Pediatric Hemophagocytic Lymphohistiocytosis. J Clin Immunol; 41(6), 1213–1218. https://doi.org/10.1007/s10875-021-01025-3.

Si SJ, Teachey DT. (2020). Spotlight on tocilizumab in the treatment of CAR T Cell-induced cytokine release syndrome: clinical evidence to date. Ther Clin Risk Manag; 19:705-714.

Si SJ, Teachey DT. (2020). The Hematologist Clinical Trials Corner: Bringing Immunotherapy to the Frontline in Childhood Leukemia. May-June; 17(3): 14-15.

Selected Poster Presentations

Miranda M, Leiding J, Tsalatsanis A, Trotter J, Arnold D, Parikh S, Marsh R, Griffith L, Mallhi K, Chellapandian D, Si SJ, Grunebaum E, Dvorak C, Kang E, Haddad E, Kohn D, Pai SY, Puck J, Pulsipher M, Torgerson T, Malech H, Sullivan K, Newburger P, Dinauer M, Notarangelo L. Self-reported Symptom Burden of Female X-linked Chronic Granulomatous Disease Carriers- a PIDTC Report. Poster Presentation, Clinical Immunology Society (CIS). Charlotte, North Carolina, 2022.

Ramos J, Si SJ, Fujii T, Haun B, Yang WS, Los G, Yu L, Jayanthan A, Dunn S. Targeting B-Raf and Checkpoint Inhibitor Resistant Melanoma with RSK inhibitor PMD-026. Poster presentation, American Association for Cancer Research (AACR), Las Vegas, Nevada, 2021.

Active Grants

S. Si Lim, PI; J. Fukui, Co-PI
NIMHD/NIH
U54 MD007601-35
“Unlocking breast cancer disparities to inform immunotherapy for Native Hawaiian women”
07/01/2021 – 06/30/2022

S. Si Lim, PI
St. Baldrick’s Foundation Infrastructure Grant (896552)
“Supporting Pediatric Cellular Therapy Cancer Research in Disparate Communities”
1/1/2022 – 12/31/2022