Nutrition Support Project

Healthy Diet and Lifestyle (HDL) Study

The HDL was a pilot study to demonstrate feasibility and explore efficacy of following an intermittent energy restriction (IER) diet over 2 contiguous days and the DASH diet for 7 contiguous days over 12 weeks to reduce visceral adipose tissue among East Asians in Hawaiʻi. The NSSR assisted with diet material preparation, participant randomization, diet consultation for the initial in-person visit and follow-up phone calls, dietary data entry for the mobile food records, and nutrient and food group analysis. The pilot provided the support to secure funding from NIH to compare the IER to continuous energy restriction using a fully powered study.

Examples of manuscripts from the HDL Study

Utility of self-rated adherence for monitoring dietary and physical activity compliance and assessment of participant feedback of the Healthy Diet and Lifestyle Study pilot. O'Reilly H, Panizza CE, Lim U, Yonemori KM, Wilkens LR, Shvetsov YB, Harvie MN, Shepherd J, Zhu FM, Le Marchand L, Boushey CJ, Cassel KD. Pilot Feasibility Stud. 2021;7(1):48. doi: 10.1186/s40814-021-00786-3. PMID: 33573693.

Effects of Intermittent Energy Restriction Combined with a Mediterranean Diet on Reducing Visceral Adiposity: A Randomized Active Comparator Pilot Study. Panizza CE, Lim U, Yonemori KM, Cassel KD, Wilkens LR, Harvie MN, Maskarinec G, Delp EJ, Lampe JW, Shepherd JA, Le Marchand L, Boushey CJ. Nutrients. 2019;11(6):1386. doi: 10.3390/nu11061386. PMID: 31226790.